Postdoctoral Position / Research Engineer - Gene Therapy for Inherited Retinal Dystrophies (F/M)

Join a translational research program focused on developing innovative gene therapy approaches for inherited retinal dystrophies. As a Postdoctoral Researcher or Research Engineer, you will work in a collaborative environment, integrating cellular models, genome editing technologies, and functional analyses. Key responsibilities include generating patient-derived iPSCs, establishing in vivo retinal disease models, and analyzing data. Candidates should have a PhD or MSc/Engineering degree in a related field, hands-on experience in molecular and cellular biology, and a strong interest in gene therapy and retinal diseases.

• Generation of patient-derived iPSCs and isogenic CRISPR-edited control lines; differentiation into retinal organoids; treatment with AAV-based gene therapy vectors.
• Establishment and maintenance of genetically engineered or pharmacological retinal disease models; in vivo administration of gene therapy vectors versus controls.
• Integration of functional, histological, and molecular datasets; contribution to mechanistic understanding of retinal gene therapy mechanisms.

### **Candidate profile**

• PhD or MSc/Engineering degree in biology, neuroscience, cell biology, or a related field ;
• Hands-on experience in molecular and cellular biology ;
• Experience in genome editing (strong asset) ;
• Experience with iPSC and/or organoid systems (strong asset) ;
• Experience with in vivo experimental models (strong asset) ;
• Strong interest in gene therapy and retinal diseases ;
• Experience with omics data analysis (RNA-seq, proteomics) is a plus ;
• Strong ability to report, structure, and communicate experimental data in a rigorous and reproducible manner ;
• Ability to present and communicate data in scientific and pharmaceutical environments, including lab meetings, internal reviews, and external conferences ;
• **Autonomy, scientific rigor, and ability to independently drive experimental work are essential.**

### **Contract**

• Position: Postdoctoral Researcher / Research Engineer ;
• Duration: 36 months ;
• Start date: flexible ;

Application : please send CV and cover letter.